An alien invasion has plunged Earth into chaos.Conventional weapons seem ineffective.In a desperate attempt to stem the tide, the American government tries out an experimental chemical treatment on five teenagers. The goal : to increase their intelligence to superhuman levels, so they can invent the weapon that will save us all. Unless they first become impossible to control...
Sasuke abandonne ses compagnons et quitte Konoha. A-t-il offert son âme à Orochimaru ?
Le nouveau Hokage ordonne à Shikamaru, récemment promu ninja de "moyenne classe", de convoquer Naruto, Neji, Kiba et Chôji pour former un commando. Ces cinq jeunes combattants (et un chien) se lancent donc à la poursuite de Sasuke.!